Change of location reduces genetic risk on mental health Research

Genes effects on mental health: : A new research has claimed that the genetic risk on your mental health also depends on where you are living. Genetic risk means that if there is any mental problem in your family i.e. either of your parents, then how much risk you are at risk from it. Researcher at King’s College London Jesse Maxwell Said that at some level a person’s genes choose their environment, and there is a reciprocal relationship between environmental and genetic influences on mental health. Therefore, whenever a model for estimating the risk of mental health is made, it should be kept in mind. The findings were published in the JAMA Psychiatry Journal. published Has happened. This research has been done in collaboration with the Maudsley Biomedical Research Center of the NIHR National Institute for Health Research.

In this study, genetic data of 3,85,793 participants of the UK Biobank were assessed in relation to mental health on the basis of PRS (Polygenic risk score). PRS measures the impact of the whole genome at the level of individual genes.

How did the study happen?
The study took British census data from 1931 to 2011. It was seen that during this time people went from which area to live in other area and how was the geographical situation there. It found that people who moved from rural areas to cities had a lower genetic risk of schizophrenia, bipolar disorder, and autism, while those who lived in rural areas had a higher risk. .

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important role of environment
Lead author of this research and Research Fellow and Consultant Psychiatrist at King’s College London Dr. Evangelos Vassos Said that “Our study provides further evidence that genetic liability for various mental disorders may contribute to a person’s environmental choices.

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Evangelos Vasos Further, these findings do not rule out the important role of the environment in the development of mental health conditions, but do suggest that we need a more integrated approach when exploring the causes of mental disorders. it occurs.

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